Drivers face six weeks of roadworks on already-congested Bootham as a new junction is installed.
City of York Council will begin the work on Monday (17 January).
This will remove the existing pedestrian crossing next to the St Mary’s junction and introduce new traffic signals.
A council spokesperson said: “The roadworks, which are expected to take approximately six weeks, will improve facilities for cyclists and pedestrians.
“The new junction will improve journeys to Scarborough Bridge and the railway station, as well as providing a signalled exit for vehicles from St Mary’s, reducing conflict at the junction.”
The working hours will be 9am to 3.30pm Monday to Friday.
Weekend working “may be necessary” but is not planned at this time. Traffic management will be undertaken using three-way temporary traffic lights.
Resurfacing will take place at the end of the period of work. It is planned for the week beginning on 21 February.
This work will be carried out by Tarmac and will be done overnight (7.30pm – 5am) to minimise disruption.
The council says: “It is usual practise that any loud activity be completed by 11pm.”
At the same time the bottom section of St Mary’s will be resurfaced, ahead of the scheme to provide a ramp access from St Mary’s to Marygate Lane.
Council transport lead Cllr Andy D’Agorne said: “Throughout 2022 and 2023 we’re working to deliver around £3.3 million to support active travel schemes across the city – making it safer and easier to travel sustainably.
“Bootham is a key arterial road into our city centre, which is why improving this route for active and sustainable transport options is vital.
“We’re grateful for residents’ patience during the work where some disruption is anticipated and look forward to the timely arrival of a new and improved junction for all road users.”